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INTRODUCTION

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Hereditary neuropathies may account for as many as 50% of previously undiagnosed peripheral neuropathies referred to large neuromuscular centers. Charcot–Marie–Tooth (CMT) disease is the most common type of hereditary neuropathy, but, rather than one disease, CMT is a syndrome of several genetically distinct disorders (Table 11-1). In this chapter, we discuss CMT and related neuropathies. In the subsequent chapters, we will review other less common hereditary neuropathies (Chapters 12, 16, and 30).

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TABLE 11-1.CLASSIFICATION OF CHARCOT–MARIE–TOOTH DISEASE AND RELATED NEUROPATHIES

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