TY  - CHAP
M1  - Book, Section
TI  - HIV NEUROLOGY
A1  - Fauci, Anthony S.
A1  - Lane, H. Clifford
A2  - Hauser, Stephen L.
A2  - Josephson, S. Andrew
PY  - 2018
T2  - Harrison's Neurology in Clinical Medicine, 4e
AB  - Clinical  disease  of  the  nervous  system  accounts  for  a  significant  degree  of  morbidity  in  a  high  percentage  of  patients  with  HIV  infection  (Table  48-1).  The  neurologic  problems  that  occur  in  HIV-infected  individuals  may  be  either  primary  to  the  pathogenic  processes  of  HIV  infection  or  secondary  to  opportunistic  infections  or  neoplasms.  Among  the  more  frequent  opportunistic  diseases  that  involve  the  CNS  are  toxoplasmosis,  cryptococcosis,  progressive  multifocal  leukoencephalopathy,  and  primary  CNS  lymphoma.  Other  less  common  problems  include  mycobacterial  infections;  syphilis;  and  infection  with  CMV,  HTLV-1,  Trypanosoma  cruzi,  or  Acanthamoeba.  Overall,  secondary  diseases  of  the  CNS  have  been  reported  to  occur  in  approximately  one-third  of  patients  with  AIDS.  These  data  antedate  the  widespread  use  of  cART,  and  this  frequency  is  considerably  lower  in  patients  receiving  effective  antiretroviral  drugs.  Primary  processes  related  to  HIV  infection  of  the  nervous  system  are  reminiscent  of  those  seen  with  other  lentiviruses,  such  as  the  Visna-Maedi  virus  of  sheep.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - neurology.mhmedical.com/content.aspx?aid=1147190361
ER  -