TY - CHAP M1 - Book, Section TI - Vasculitic Neuropathies A1 - Amato, Anthony A. A1 - Russell, James A. Y1 - 2015 N1 - T2 - Neuromuscular Disorders, 2e AB - Vasculitis is an immune-mediated disorder directed against blood vessels, which results in ischemia to end organs supplied by the affected blood vessels.1–5 The vasculitides can be distinguished and classified based on at least three nosologic categories. They can be differentiated based on the caliber of vessel involved (i.e., small, medium, or large vessel). They can be distinguished on whether the disorder is primary [e.g., polyarteritis nodosa (PAN), microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GAN, formerly known as Wegener granulomatosis), and Churg–Strauss syndrome (CSS)] or secondary to other systemic disorders (e.g., connective tissue disease, malignancy, infection, or drug reaction). Furthermore, the vasculitides can be separated based on whether they are systemic or isolated to the peripheral nervous system (PNS), and if associated with antineutrophil cytoplasmic antibodies (ANCAs) (Table 15-1).2,3 Vasculitis is much more common in adults but can develop in children.6 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - neurology.mhmedical.com/content.aspx?aid=1115658511 ER -