TY - CHAP M1 - Book, Section TI - Other Disorders of Neuromuscular Transmission A1 - Amato, Anthony A. A1 - Russell, James A. PY - 2015 T2 - Neuromuscular Disorders, 2e AB - This chapter describes the disorders of neuromuscular transmission (DNMT) other than myasthenia gravis (MG) (Table 26-1). The neuromuscular junction (NMJ) is a physiologically complex structure. Its ability to function optimally requires the integration of a large number of proteins including ion channels that are correctly configured and distributed. As a result of numerous potential sites of vulnerability, DNMTs may occur as a consequence of multiple, albeit infrequent disorders. Autoimmune, genetic, or toxic mechanisms may disrupt the ultrastructure or physiology of the NMJ, thus interfering with effective NMT. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - neurology.mhmedical.com/content.aspx?aid=1115660550 ER -