RT Book, Section
A1 Boland, Robert
A1 Haimovici, Florina
A1 Oser, Megan
A1 Mirsky, Pamela
A1 Korzinek, Joshua
A2 Barsky, Arthur J.
A2 Silbersweig, David A.
A2 Boland, Robert J.
SR Print(0)
ID 1138126113
T1 Depression and Gastrointestinal Disease
T2 Depression in Medical Illness
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071819084
LK neurology.mhmedical.com/content.aspx?aid=1138126113
RD 2024/04/19
AB Psychiatry  has  enjoyed  a  particularly  interesting  relationship  with  the  gastrointestinal  (GI)  illnesses  since  the  brain–gut  relationship  was  considered  one  of  the  core  examples  of  how  psychological  stress  could  influence  autonomic  processes,1  until  increasing  understanding  regarding  the  pathophysiology  underlying  stomach  and  duodenal  disorders  diminished  interest  in  this  relationship.  Still,  it  remains  a  fact  that  the  brain  and  digestive  tract  are  intimately  connected  and  more  recent—and  more  modest—research  reveals  strong  evidence  for  direct  and  indirect  influences  of  one  on  the  other.  Considering  that  depression  can  be  a  consequence  of  both  physiological  and  psychological  stress,  it  should  be  no  surprise  that  depressive  disorders  very  commonly  co-occur  with  GI  disorders.  This  chapter  will  consider  several  examples  of  the  complex  relationship  between  depressive  disorders  and  GI  disorders,  including  peptic  ulcer  disease,  irritable  bowel  syndrome  (IBS),  inflammatory  bowel  disease  (IBD),  and  various  diseases  of  the  liver.