RT Book, Section A1 Hartman, Adam L. A1 Morrison, Peter F. A1 Vining, Eileen P. A2 Sirven, Joseph I. A2 Stern, John M. SR Print(0) ID 1103050443 T1 Epilepsia Partialis Continua T2 Atlas of Video-EEG Monitoring YR 2011 FD 2011 PB McGraw-Hill Education PP New York, NY SN 9780071597425 LK neurology.mhmedical.com/content.aspx?aid=1103050443 RD 2024/04/23 AB Epilepsia partialis continua (EPC) is a rare presentation of epilepsy, but its recognition is important because it may be the harbinger of very serious disease. EPC was described by the International League Against Epilepsy as involving nonprogressive localized partial motor seizures followed by myoclonus at a later point in time.1 It is characterized by sustained and persistent repetitive focal motor activity, usually described as clonic or myoclonic in nature, typically involving a limited number of muscle groups. Both agonist and antagonist muscle groups can be involved, with any frequency, and it can persist to some degree in sleep. The face, shoulder, arm, and hand are most commonly affected (Videos 27-1, 27-2, 27-3, 27-4, and 27-5). The movement may have an arrhythmic character. Some patients report seizures worsening during activities, such as moving to pick up an object. In these cases, seizure exacerbations as the hand nears the target may be suggestive of an intention tremor, but the larger amplitude in EPC usually distinguish the two types of movements.