RT Book, Section
A1 Amato, Anthony A.
A1 Russell, James A.
SR Print(0)
ID 1115656581
T1 Muscle and Nerve Histopathology
T2 Neuromuscular Disorders, 2e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071752503
LK neurology.mhmedical.com/content.aspx?aid=1115656581
RD 2024/04/25
AB Muscle  and  nerve  biopsies  can  be  extremely  useful  in  the  evaluation  of  patients  with  myopathies  and  neuropathies.  That  said,  not  everyone  suspected  of  having  a  muscle  or  nerve  disorder  needs  a  biopsy.  In  this  chapter,  we  discuss  the  indications  and  limitations  for  muscle  and  nerve  biopsies,  how  specific  muscle  or  nerves  are  selected  for  biopsy,  and  various  aspects  of  specimen  handling.  Further,  we  review  the  routine  stains  that  are  performed  on  muscle  and  nerve  tissue,  other  stains  or  studies  that  can  be  performed  on  the  tissue,  and  when  to  order  them.  We  also  mention  the  role  of  skin  biopsy  to  assess  epidermal  nerve  fibers  in  the  evaluation  of  patients  with  peripheral  neuropathy.  This  chapter  is  not  designed  to  make  the  reader  a  neuropathologist.  However,  clinicians  who  take  care  of  patients  with  neuromuscular  disease  and  order  biopsies  should  have  at  least  a  working  knowledge  of  muscle  and  nerve  histopathology.