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Principles of Neural Science, Fifth Edition Copyright © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. Printed in the United States of America. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a data base or retrieval system, without the prior written permission of the publisher.

Previous editions copyright © 2000 by McGraw-Hill Companies; © 1991 by Appleton & Lange.

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ISBN 978-0-07-139011-8

MHID 0-07-139011-1

This book was set in Palatino by Cenveo Publisher Services.

The editors were Anne Sydor and Harriet Lebowitz.

The production supervisor was John Williams.

The art manager was Armen Ovsepyan.

The illustrators were Precision Graphics.

The editorial manager was Clayton Eccard.

The art consultant was Eve Siegel.

Project management was provided by Rajni Pisharody, Cenveo Publisher Services.

RR Donnelley was printer and binder.

This book is printed on acid-free paper.

Cover image: This image is a lithograph by F. Schima from a drawing by Sigmund Freud of the spinal ganglion of the lamprey Petromyzon. Before he discovered the unconscious, Freud had a promising career as a neural scientist. The cover thus recognizes that, a century after Freud's discovery, progress in the study of cognition has reemphasized the importance of unconscious mental processes for perception and action. (Reproduced, with permission, from Sigmund Freud, “Über Spinalganglien und R¨ckenmark der Petromyzon,” Sitzungsberichte der Mathematisch-Naturwissenschaftlichen Classe der Kaiserlichen Akademie der Wissenschaften, LXXVIII. Band I. Abtheilung, 1878, copyright New York Academy of Medicine.)

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