TY - CHAP M1 - Book, Section TI - Coma and Other States of Altered Consciousness A1 - Robinson, Christopher A1 - Wijdicks, Eelco A2 - Salardini, Arash A2 - Biller, José PY - 2016 T2 - The Hospital Neurology Book AB - Abnormal consciousness is caused by pathologies that specifically alter the function of a neuronal network responsible for causing awareness and alertness. Understanding of the basic concepts of this arousal system and the pathophysiologic mechanisms underlying its alteration are imperative in the diagnosis, treatment, and long-term management of coma. This chapter will focus on the definition of consciousness, the physiology of arousal, the pathologies underlying coma, the neurologic examination of the comatose patient, management of coma, and assessment of prognosis. Each section is accompanied by a case to illustrate the different clinical scenarios in which coma can present. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - neurology.mhmedical.com/content.aspx?aid=1127047226 ER -