TY - CHAP M1 - Book, Section TI - Novel Opioid Formulations A1 - Webster, Lynn R. A2 - Bajwa, Zahid H. A2 - Wootton, R. Joshua A2 - Warfield, Carol A. PY - 2016 T2 - Principles and Practice of Pain Medicine, 3e AB - The medical profession recognizes the clinical value of prescribed opioids in treating noncancer pain that is persistent and recalcitrant to other therapies.1 However, the clinical benefit of conventional opioid formulations falls short of the need. Although analgesia from opioids is often limited to a subset of patients who achieve benefit, long-term analgesic efficacy is uncertain, and discontinuation of therapy due to adverse events or inadequate analgesia is common.2 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/12 UR - neurology.mhmedical.com/content.aspx?aid=1131936848 ER -