TY - CHAP M1 - Book, Section TI - Depression and Substance Use Disorders A1 - Suzuki, Joji A2 - Barsky, Arthur J. A2 - Silbersweig, David A. A2 - Boland, Robert J. PY - 2016 T2 - Depression in Medical Illness AB - The comorbidity of major depression and substance use disorder (SUD), which includes both alcohol and drugs, remains very common in medical and psychiatric settings (Fig. 19-1).1–3 Both major depression and SUD are among of the most common psychiatric disorders, each leading to significant morbidity and mortality and placing a heavy burden on the health care system.4 In clinical settings, however, SUDs are often underdiagnosed or missed entirely. Even if the SUD is correctly identified, treatment is often inadequate or not offered at all.5,6 Studies have consistently noted that patients with both depression and SUD present with worse symptoms and have poorer outcomes, including a higher incidence of suicide attempts, than patients with either disorder alone (Fig. 19-2).7,8 Research on the dually diagnosed population is still in its early stages, and significant gaps still remain.9 Research on the comorbidity between dual diagnosis and medical illness is even less frequently studied. Nevertheless, when approaching a depressed patient with comorbid SUD, clinicians need to be aware of the specific issues unique to this population. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - neurology.mhmedical.com/content.aspx?aid=1138126729 ER -