TY - CHAP M1 - Book, Section TI - Impact of Comorbidities on Health Outcomes A1 - Friedman, David A1 - Gillaim, Frank G. A2 - Duchowny, Michael A2 - Cross, J. Helen A2 - Arzimanoglou, Alexis PY - 2017 T2 - Pediatric Epilepsy AB - The World Health Organization defines health as "a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity."1 In the past, measures of success in treating medical illness have been thought of in terms of freedom of disease or identifiable quantifiable endpoints, such as serum glucose, systolic blood pressure, or seizures.2 However, recently, there has been an emergence of interest in measuring health-related quality of life (HRQOL), a valid and significant indicator of health in patients with disease. This idea has been studied over the past decade and applied to develop reliable and valid measures of function and well-being for use in patients with epilepsy.3 This concept especially pertains to chronic epilepsy, where though many treating clinicians focus on treating the ictal phenomenon of the disease, namely seizures, the disease itself carries a multitude of clinically relevant interictal comorbidities that affects patients' overall HRQOL. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/10 UR - neurology.mhmedical.com/content.aspx?aid=1138411914 ER -