TY  - CHAP
M1  - Book, Section
TI  - Antiepileptic Drugs: How to Choose
A1  - Pellock, John M.
A2  - Duchowny, Michael
A2  - Cross, J. Helen
A2  - Arzimanoglou, Alexis
PY  - 2017
T2  - Pediatric Epilepsy
AB  - Following  the  diagnosis  of  epilepsy  and  making  the  decision  to  start  a  treatment,  as  discussed  in  the  prior  chapter,  the  clinician  must  choose  the  most  appropriate  initial  medication.  This  decision  requires  knowledge  of  the  clinical  pharmacology  of  medications  used  for  the  treatment  of  epilepsy  and  an  ability  to  individualize  treatment  to  the  child  in  question.1  The  ultimate  goal  is  complete  control  of  seizures  without  producing  adverse  effects.  Although  the  perfect  drug  does  not  exist,  the  current  therapeutic  armamentarium  offers  a  broader  range  of  choices  than  available  ever  before  with  each  drug  having  some  advantages  and  disadvantages.  A  single  drug  should  be  chosen  so  that  the  child  is  treated  with  monotherapy,  which  has  the  likelihood  of  producing  the  fewest  number  of  side  effects.2,3  The  first  issue  in  deciding  upon  initial  therapy  depends  on  seizure  type.  An  appreciation  of  epilepsy  syndrome  is  also  extremely  important,  as  it  may  select  for  or  against  an  agent  and  may  exacerbate  seizure  types,  which  have  not  been  yet  appreciated  in  the  child.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/20
UR  - neurology.mhmedical.com/content.aspx?aid=1138411988
ER  -