TY - CHAP M1 - Book, Section TI - Women’s Neuropsychiatry A1 - Salama, Kate A1 - O’Neal, Mary A1 - Nathan, Margo A1 - Mittal, Leena A2 - Silbersweig, David A. A2 - Safar, Laura T. A2 - Daffner, Kirk R. PY - 2021 T2 - Neuropsychiatry and Behavioral Neurology: Principles and Practice AB - Women’s neurology and mental health are defined as the study of neurologic and psychiatric disorders approached through a sex-based lens. This chapter will discuss some of the sex-based differences in neurologic and psychiatric disorders. The specific concerns vary depending on the disorder, where the woman is in her reproductive cycle, and her psychosocial milieu. The neurologic diseases to be reviewed are those with significant sex differences in prevalence, clinical presentation, or management. They include systemic lupus erythematosus (SLE), migraine, epilepsy, anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis, stroke, and Alzheimer’s disease (AD). The psychiatric disorders to be discussed will include those that are related to, or influenced by, the reproductive events in a woman’s life—including perimenstrual disorders, perinatal disorders, and perimenopausal disorders. We will focus on these periods of increased hormonal variability and discuss the relationship between sex hormones and serotonergic, dopaminergic, GABAergic, and glutamatergic transmission, and other neurobiological factors. While the focus of this chapter is on the sex differences in epidemiology, clinical features, pathophysiology, and treatment of many neurologic and psychiatric disorders, it is important to note that these same disorders are covered in detail in other chapters of this textbook. We direct the reader to the specific chapters, as appropriate, within each of the subtitles below. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/29 UR - neurology.mhmedical.com/content.aspx?aid=1178765035 ER -