TY - CHAP M1 - Book, Section TI - Motor Neuron Disease A1 - Tian, Cuixia A2 - Hershey, Andrew D. PY - 2023 T2 - CURRENT Diagnosis & Treatment Pediatric Neurology AB - Motor neuron diseases are a group of rare diseases affecting spinal motor neurons. They clinically present with progressive degenerative muscle weakness and wasting and lead to impairment in mobility, speech, swallowing, and breathing functions. Spinal muscular atrophy (SMA) is the leading cause for motor neuron disease in children. Here, we focus on SMAs, including the most common SMA, also known as proximal or 5q-SMA, as well as atypical SMA, also known as SMA plus, especially riboflavin-responsive motor neuron disease, which is a treatable childhood-onset motor neuron disease. SN - PB - McGraw Hill Education CY - New York, NY Y2 - 2024/03/29 UR - neurology.mhmedical.com/content.aspx?aid=1195238228 ER -