TY - CHAP M1 - Book, Section TI - Chapter 33. Clinical Features and Treatment of Huntington's Disease A1 - Wahlster, Sarah A1 - Cha, Jang-Ho J. A2 - Watts, Ray L. A2 - Standaert, David G. A2 - Obeso, Jose A. PY - 2012 T2 - Movement Disorders, 3e AB - Chorea is essentially a disease of the nervous system. The name “chorea” is given to the disease on account of the dancing propensities of those who are affected by it, and it is a very appropriate designation...The hereditary chorea, as I shall call it, is confined to certain and fortunately a few families, and has been transmitted to them, an heirloom from generations away back in the dim past. It is spoken of by those in whose veins the seeds of the disease are known to exist, with a kind of horror, and not at all alluded to except, through dire necessity, when it is mentioned as “that disorder.” It is attended generally by all the symptoms of common chorea, only in an aggravated degree, hardly ever manifesting itself until adult or middle life, and then coming on gradually but surely, increasing by degrees, and often occupying years in its development, until the hapless sufferer is but a quivering wreck of his former self...I have never known a recovery or even an amelioration of symptoms in this form of chorea; when once it begins it clings to the bitter end.—George Huntington, 18721 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - neurology.mhmedical.com/content.aspx?aid=55800552 ER -