TY - CHAP M1 - Book, Section TI - Muscle and Nerve Histopathology A1 - Amato, Anthony A. A1 - Russell, James A. PY - 2015 T2 - Neuromuscular Disorders, 2e AB - Muscle and nerve biopsies can be extremely useful in the evaluation of patients with myopathies and neuropathies. That said, not everyone suspected of having a muscle or nerve disorder needs a biopsy. In this chapter, we discuss the indications and limitations for muscle and nerve biopsies, how specific muscle or nerves are selected for biopsy, and various aspects of specimen handling. Further, we review the routine stains that are performed on muscle and nerve tissue, other stains or studies that can be performed on the tissue, and when to order them. We also mention the role of skin biopsy to assess epidermal nerve fibers in the evaluation of patients with peripheral neuropathy. This chapter is not designed to make the reader a neuropathologist. However, clinicians who take care of patients with neuromuscular disease and order biopsies should have at least a working knowledge of muscle and nerve histopathology. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/04 UR - neurology.mhmedical.com/content.aspx?aid=1115656581 ER -