TY - CHAP M1 - Book, Section TI - Disorders of Motility: Introduction A1 - Ropper, Allan H. A1 - Samuels, Martin A. A1 - Klein, Joshua P. A1 - Prasad, Sashank Y1 - 2019 N1 - T2 - Adams and Victor's Principles of Neurology, 11e AB - The control of motor function, to which much of the human nervous system is committed, is accomplished through the integrated action of a vast array of segmental and suprasegmental motor neurons. As originally conceived by Hughlings Jackson in 1858, purely on the basis of clinical observations, the motor system is organized hierarchically in three levels, each higher level controlling the one below. It was Jackson’s concept that the spinal and brainstem neurons represent the lowest, simplest, and most highly organized motor centers; that the motor neurons of the posterior frontal region represent a more complex and less closely organized second motor center; and that the prefrontal parts of the cerebrum are the third and highest motor center. This scheme is still regarded as being essentially correct, although since Jackson’s time the importance of the parietal lobe and basal ganglia in motor control has been recognized. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - neurology.mhmedical.com/content.aspx?aid=1162601619 ER -