TY - CHAP M1 - Book, Section TI - Depression and Gastrointestinal Disease A1 - Boland, Robert A1 - Haimovici, Florina A1 - Oser, Megan A1 - Mirsky, Pamela A1 - Korzinek, Joshua A2 - Barsky, Arthur J. A2 - Silbersweig, David A. A2 - Boland, Robert J. Y1 - 2016 N1 - T2 - Depression in Medical Illness AB - Psychiatry has enjoyed a particularly interesting relationship with the gastrointestinal (GI) illnesses since the brain–gut relationship was considered one of the core examples of how psychological stress could influence autonomic processes,1 until increasing understanding regarding the pathophysiology underlying stomach and duodenal disorders diminished interest in this relationship. Still, it remains a fact that the brain and digestive tract are intimately connected and more recent—and more modest—research reveals strong evidence for direct and indirect influences of one on the other. Considering that depression can be a consequence of both physiological and psychological stress, it should be no surprise that depressive disorders very commonly co-occur with GI disorders. This chapter will consider several examples of the complex relationship between depressive disorders and GI disorders, including peptic ulcer disease, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and various diseases of the liver. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - neurology.mhmedical.com/content.aspx?aid=1138126113 ER -