TY - CHAP M1 - Book, Section TI - Depression in Sleep Disorders A1 - Mackie, Susan A1 - Winkelman, John A2 - Barsky, Arthur J. A2 - Silbersweig, David A. A2 - Boland, Robert J. Y1 - 2016 N1 - T2 - Depression in Medical Illness AB - The study of human sleep is a remarkably young field. Until the 1930s, sleep was viewed as a passive state during which the brain was “turned off.” As such, there was little interest in further characterization of normal sleep or exploration of sleep disorders. In 1937, A. L. Loomis first described the characteristic electroencephalographic patterns of the stages of NREM sleep, challenging the notion of sleep as a homogeneous and passive state.1 This was followed in 1951 by the discovery of REM sleep and its correlation with dreaming.2 A schema of sleep architecture consisting of repeated cycles of NREM and REM sleep was formulated shortly thereafter, a concept that has persisted largely unchanged into the modern era of sleep medicine. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - neurology.mhmedical.com/content.aspx?aid=1138126657 ER -