TY - CHAP M1 - Book, Section TI - Hemispheric Disorders Associated with Cortical Malformation A1 - Duchowny, Michael A2 - Duchowny, Michael A2 - Cross, J. Helen A2 - Arzimanoglou, Alexis Y1 - 2017 N1 - T2 - Pediatric Epilepsy AB - Disorders of neurogenesis, neuronal maturation, and proliferation are responsible for many severe forms of childhood epilepsy. They may arise in discrete cortical areas or involve widespread brain regions in one or both cerebral hemispheres. While extensive unilateral involvement of one cerebral hemisphere is a relatively uncommon condition, the rare occurrence of a hemispheric malformation is associated with a high rate of morbidity and mortality. Affected children typically manifest cognitive delay, intractable epileptic seizures, and lateralized neurological deficits. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/23 UR - neurology.mhmedical.com/content.aspx?aid=1138411394 ER -