TY  - CHAP
M1  - Book, Section
TI  - Myasthenia Gravis & Other Disorders of the Neuromuscular Junction
A1  - Faktorovich, Svetlana
A1  - Patterson, Shanna K.
A2  - Brust, John C.M.
Y1  - 2019
N1  - 
T2  - CURRENT Diagnosis & Treatment: Neurology, 3e
AB  - The  neuromuscular  junction  is  the  synaptic  connection  formed  between  a  motor  neuron  axon  and  the  muscle  fiber  it  innervates.  The  transmitter  used  at  the  neuromuscular  junction,  acetylcholine,  is  stored  in  the  presynaptic  motor  nerve  terminals.  The  postsynaptic  muscle  membrane  has  many  folds  in  which  receptors  for  acetylcholine  are  located.  When  a  motor  nerve  action  potential  reaches  the  presynaptic  nerve  terminal,  there  is  a  resultant  increase  in  calcium  conductance  through  voltage-gated  calcium  channels.  This  increase  in  intracellular  calcium  leads  to  the  fusion  of  acetylcholine-filled  presynaptic  vesicles  with  the  plasma  membrane  of  the  motor  nerve  terminal.  Acetylcholine  is  subsequently  released  into  the  synaptic  cleft  by  exocytosis.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/23
UR  - neurology.mhmedical.com/content.aspx?aid=1159971355
ER  -