TY - CHAP M1 - Book, Section TI - Focal Neurobehavioral Syndromes A1 - Erkkinen, Michael A1 - Putcha, Deepti A1 - Daffner, Kirk R. A2 - Silbersweig, David A. A2 - Safar, Laura T. A2 - Daffner, Kirk R. Y1 - 2021 N1 - T2 - Neuropsychiatry and Behavioral Neurology: Principles and Practice AB - One of the fundamental working hypotheses of modern neuroscience is that the functioning of the brain permits and shapes the expression of the mind. Cognitive, perceptual, affective, and behavioral capacities and limits are determined by neural structures and the dynamic flow of information within them. The shifting contents of momentary experience are the product of precisely coordinated, ever-changing combinations of electrical activity within richly connected neural networks. Put another way, neural states encode mental experiences. These complex neurobiological processes are scaffolded by evolution via inherited factors, animated by environmental inputs, and chiseled by experience and learning. The system learns about itself and the workings of its environment through continuous prediction and feedback, self-generated actions and environmental inputs shape this dynamic neural circuitry. Brain-behavior relationships are complex but patterned: specific neural activities support specific mental states and localized brain dysfunction leads to focal neurobehavioral changes. This schematic framework relating brain and mind is embedded in the clinical fields of behavioral neurology and neuropsychiatry and serves as this chapter’s main axiom. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/24 UR - neurology.mhmedical.com/content.aspx?aid=1178762119 ER -