TY - CHAP M1 - Book, Section TI - Experience and the Refinement of Synaptic Connections Y1 - 2014 N1 - T2 - Principles of Neural Science, Fifth Edition AB - Development of Human Mental Function Is Influenced by Early ExperienceEarly Experience Has Lifelong Effects on Social BehaviorsDevelopment of Visual Perception Requires Visual ExperienceDevelopment of Binocular Circuits in the Visual Cortex Depends on Postnatal ActivityVisual Experience Affects the Structure and Function of the Visual CortexPatterns of Electrical Activity Organize Binocular Circuits in the Visual CortexReorganization of Visual Circuits During a Critical Period Involves Alterations in Synaptic ConnectionsReorganization Depends on a Change in the Balance of Excitatory and Inhibitory InputsPostsynaptic Structures Are Rearranged During the Critical PeriodThalamic Inputs Are Also RemodeledSynaptic Stabilization Contributes to Closing the Critical PeriodSegregation of Retinal Inputs in the Lateral Geniculate Nucleus Is Driven by Spontaneous Neural Activity In UteroActivity-Dependent Refinement of Connections Is a General Feature of Circuits in the Central Nervous SystemMany Aspects of Visual System Development Are Activity-DependentAuditory Maps Are Refined During a Critical PeriodDistinct Regions of the Brain Have Different Critical Periods of DevelopmentCritical Periods Can Be Reopened in AdulthoodAn Overall View SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - neurology.mhmedical.com/content.aspx?aid=1101683550 ER -