TY - CHAP M1 - Book, Section TI - Generalized Seizures in Early Childhood (2–4 Years of Age) A1 - Kessler, Sudha K. A1 - Dlugos, Dennis J. A2 - Duchowny, Michael A2 - Cross, J. Helen A2 - Arzimanoglou, Alexis PY - 2017 T2 - Pediatric Epilepsy AB - As discussed in Chapter 1, classification of epileptic seizure types has practical importance but also significant limitations. Historically used terms may not accurately reflect the complex pathophysiology or phenomenology of seizures. Generalized seizures involve synchronous epileptic discharges throughout the cerebral cortex, and are further distinguished by the terms primary or secondarily. Seizures that appear to have synchronous bihemispheric involvement at initiation (based on clinical and electrographic evidence) are primary generalized seizures and those that begin in a focal area of cortex and subsequently spread to involve both hemispheres are secondarily generalized. This distinction is not always straightforward, and a high index of suspicion should be maintained for focal onset seizures that appear generalized, because evaluation and treatment differs between generalized and focal epilepsies. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - neurology.mhmedical.com/content.aspx?aid=1138409836 ER -