TY - CHAP M1 - Book, Section TI - The Role of ECMO in Cardiopulmonary Failure in Adults A1 - Abrams, Darryl A1 - Brodie, Daniel A2 - Lee, Kiwon PY - 2017 T2 - The NeuroICU Book, 2e AB - A 45-year-old man is admitted to the neurologic intensive care unit (NeuroICU) after resection of a craniopharyngioma. Three days into his ICU admission, he has a witnessed aspiration event with subsequent respiratory distress and hypoxemia requiring invasive mechanical ventilation. Over the next 24 hours, his hypoxemic respiratory failure worsens despite increasing mechanical ventilatory support, deep sedation, neuromuscular blockade, and a trial of prone positioning. His chest radiograph demonstrates diffuse bilateral infiltrates. With the patient receiving a fraction of inspired oxygen of 1.0, a positive end-expiratory pressure of 15 cm H2O, a tidal volume of 6 mL/kg of predicted body weight, and a respiratory rate of 35 breaths per minute, arterial blood gas analysis reveals a pH of 7.14, a PaCO2 of 70 mm Hg, and a PaO2 of 50 mm Hg. Plateau airway pressure, measured at end inspiration, is 37 cm H2O. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - neurology.mhmedical.com/content.aspx?aid=1143957056 ER -