TY - CHAP M1 - Book, Section TI - Muscular Dystrophies A1 - Amato, Anthony A. A1 - Russell, James A. PY - 2015 T2 - Neuromuscular Disorders, 2e AB - Muscular dystrophies are hereditary, progressive muscle diseases in which there is necrosis of muscle tissue and replacement by connective and fatty tissues, which helps to distinguish them from other hereditary myopathies. Before discussing specific types of muscular dystrophies, it is important to have an understanding of the relevant muscle proteins that are affected in the various dystrophies. The different forms of muscular dystrophies result from mutations affecting proteins localizable to the sarcolemma, myonuclei, basement membrane and extracellular matrix surrounding muscle fibers, sarcomere and nonstructural enzymatic proteins.1,2 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - neurology.mhmedical.com/content.aspx?aid=1115661187 ER -