RT Book, Section A1 Ropper, Allan H. A1 Samuels, Martin A. A1 Klein, Joshua P. A1 Prasad, Sashank SR Print(0) ID 1162601619 T1 Disorders of Motility: Introduction T2 Adams and Victor's Principles of Neurology, 11e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071842617 LK neurology.mhmedical.com/content.aspx?aid=1162601619 RD 2024/04/25 AB The control of motor function, to which much of the human nervous system is committed, is accomplished through the integrated action of a vast array of segmental and suprasegmental motor neurons. As originally conceived by Hughlings Jackson in 1858, purely on the basis of clinical observations, the motor system is organized hierarchically in three levels, each higher level controlling the one below. It was Jackson’s concept that the spinal and brainstem neurons represent the lowest, simplest, and most highly organized motor centers; that the motor neurons of the posterior frontal region represent a more complex and less closely organized second motor center; and that the prefrontal parts of the cerebrum are the third and highest motor center. This scheme is still regarded as being essentially correct, although since Jackson’s time the importance of the parietal lobe and basal ganglia in motor control has been recognized.