RT Book, Section
A1 Keel, John C.
A1 Lavelle, John M.
A2 Bajwa, Zahid H.
A2 Wootton, R. Joshua
A2 Warfield, Carol A.
SR Print(0)
ID 1131930441
T1 Inflammation in Pain Disorders
T2 Principles and Practice of Pain Medicine, 3e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071766838
LK neurology.mhmedical.com/content.aspx?aid=1131930441
RD 2024/04/19
AB Pain  is  indeed  an  unpleasant  experience;  the  perception  of  pain  feels  like  damage  or  injury.  Whether  such  damage  is  actual  or  potential,  pain  is  usually  described  with  the  idioms  of  injury,  including  inflammation.  The  word  itself  conjures  flames,  fire,  burning,  redness,  swelling…ouch!  As  students  of  the  body,  we  know  that  inflammation  refers  to  a  complex  biochemical  process  and  is  not  a  colloquialism  to  be  used  loosely.  How  often  do  patients  describe  their  pain  as  swelling  or  fire,  or  ask  “is  it  inflammation?”  or  “will  this  injection  make  the  disc  swelling  go  down?”  How  often  are  treatments  variations  of  anti-inflammatories?  Is  inflammation  truly  there?  This  chapter  serves  as  a  review  of  evidence  that  there  is  a  process  of  inflammation  involved  in  some  of  the  major  conditions  seen  in  the  pain  clinic:  musculoskeletal  pain  and  neuropathic  pain.  The  general  principles  applicable  are  illustrated  in  detail  by  the  specific  examples  of  intervertebral  disc  disorders  and  complex  regional  pain  syndrome.