RT Book, Section A1 Berkowitz, Aaron L. SR Print(0) ID 1160205681 T1 Disorders of the Neuromuscular Junction T2 Clinical Neurology and Neuroanatomy: A Localization-Based Approach YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259834400 LK neurology.mhmedical.com/content.aspx?aid=1160205681 RD 2024/10/14 AB At the neuromuscular junction motor neurons release acetylcholine that binds to acetylcholine receptors on the postsynaptic muscle fibers, causing them to contract. Diseases of the neuromuscular junction can be classified as either presynaptic (e.g., Lambert-Eaton syndrome, botulism) or postsynaptic (e.g., myasthenia gravis) (Fig. 29–1). Congenital myasthenia gravis can be caused by mutations in either presynaptic or postsynaptic neuromuscular junction structures.