RT Book, Section
A1 Berkowitz, Aaron L.
SR Print(0)
ID 1160205681
T1 Disorders of the Neuromuscular Junction
T2 Clinical Neurology and Neuroanatomy: A Localization-Based Approach
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9781259834400
LK neurology.mhmedical.com/content.aspx?aid=1160205681
RD 2024/04/19
AB At  the  neuromuscular  junction  motor  neurons  release  acetylcholine  that  binds  to  acetylcholine  receptors  on  the  postsynaptic  muscle  fibers,  causing  them  to  contract.  Diseases  of  the  neuromuscular  junction  can  be  classified  as  either  presynaptic  (e.g.,  Lambert-Eaton  syndrome,  botulism)  or  postsynaptic  (e.g.,  myasthenia  gravis)  (Fig.  29–1).  Congenital  myasthenia  gravis  can  be  caused  by  mutations  in  either  presynaptic  or  postsynaptic  neuromuscular  junction  structures.