RT Book, Section A1 Connolly, Mary B. A2 Duchowny, Michael A2 Cross, J. Helen A2 Arzimanoglou, Alexis SR Print(0) ID 1138409959 T1 Benign Myoclonic Epilepsy in Infancy T2 Pediatric Epilepsy YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071496216 LK neurology.mhmedical.com/content.aspx?aid=1138409959 RD 2024/10/04 AB Benign myoclonic epilepsy in infancy (BMEI), first described by Dravet and Bureau in 1981, is a rare epilepsy syndrome.1 It is classified among the idiopathic generalized epilepsies and typically begins by the age of 3 years.2 BMEI is characterized by brief myoclonic seizures without other seizure types in developmentally normal children. The myoclonic seizures may occur spontaneously or be provoked by contact or noise. A history of simple febrile seizures may be present. In a series of 88 patients with BMEI, 26.1% had a history of simple febrile seizures.3 There is a family history of epilepsy or febrile seizures in 50% or more of patients. Myoclonic seizures are easily controlled with medication and usually remit later in childhood. Generalized tonic–clonic seizures may occur in late childhood or adolescence. Neurodevelopmental outcome is variable; most children have normal development but may experience educational difficulties.