RT Book, Section A1 Fejerman, Natalio A1 Gobbi, Giuseppe A1 Grosso, Salvatore A2 Duchowny, Michael A2 Cross, J. Helen A2 Arzimanoglou, Alexis SR Print(0) ID 1138410655 T1 Benign Epilepsy with Centrotemporal Spikes (BECTS) T2 Pediatric Epilepsy YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071496216 LK neurology.mhmedical.com/content.aspx?aid=1138410655 RD 2024/03/28 AB Benign childhood epilepsy with centrotemporal spikes (BCECTS) is among the most frequent benign focal epilepsies in childhood and accounts for about 15%–25% of all epileptic syndromes in children with ages between 4 and 12 years.1 The annual incidence ranges between 7.1 and 21 per 100,000 in children under the age of 15 years2 with a slight male predominance.3 Absence of neurological and intellectual deficits are part of the definition, even though BCECTS has also been reported in patients with neuroradiologically documented cerebral lesions.4,5 Genetic factors play an important etiological role, as corroborated by the higher incidence of positive family history for epilepsy and focal electroencephalographic (EEG) abnormalities in BCECTS patients.6 Linkage to chromosome 15q14 was pointed out,7 but not confirmed in several studies.8