RT Book, Section A1 Doty, Richard L. A1 Bromley, Steven M. A2 Hauser, Stephen L. A2 Josephson, S. Andrew SR Print(0) ID 1145768783 T1 DISORDERS OF SMELL AND TASTE T2 Harrison's Neurology in Clinical Medicine, 4e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259835865 LK neurology.mhmedical.com/content.aspx?aid=1145768783 RD 2024/04/24 AB All environmental chemicals necessary for life enter the body by the nose and mouth. The senses of smell (olfaction) and taste (gustation) monitor such chemicals, determine the flavor and palatability of foods and beverages, and warn of dangerous environmental conditions, including fire, air pollution, leaking natural gas, and bacteria-laden foodstuffs. These senses contribute significantly to quality of life and, when dysfunctional, can have untoward physical and psychological consequences. A basic understanding of these senses in health and disease is critical for the physician, because thousands of patients present to doctors’ offices each year with complaints of chemosensory dysfunction. Among the more important recent developments in neurology is the discovery that decreased smell function is among the first signs, if not the first sign, of such neurodegenerative diseases as Parkinson’s disease (PD) and Alzheimer’s disease (AD), signifying their “presymptomatic” phase.