RT Book, Section A1 Koroshetz, Walter J. A1 Nath, Avindra A2 Hauser, Stephen L. A2 Josephson, S. Andrew SR Print(0) ID 1147190306 T1 CHRONIC AND RECURRENT MENINGITIS T2 Harrison's Neurology in Clinical Medicine, 4e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259835865 LK neurology.mhmedical.com/content.aspx?aid=1147190306 RD 2024/03/28 AB Chronic inflammation of the meninges (pia, arachnoid, and dura) can produce profound neurologic disability and may be fatal if not successfully treated. Chronic meningitis is diagnosed when a characteristic neurologic syndrome exists for >4 weeks and is associated with a persistent inflammatory response in the cerebrospinal fluid (CSF) (white blood cell count >5/μL). The causes are varied, and appropriate treatment depends on identification of the etiology. Five categories of disease account for most cases of chronic meningitis: (1) meningeal infections, (2) malignancy, (3) autoimmune inflammatory disorders, (4) chemical meningitis, and (5) parameningeal infections.