RT Book, Section A1 Mello, Nancy K. A1 Mendelson, Jack H. A2 Hauser, Stephen L. A2 Josephson, S. Andrew SR Print(0) ID 1147191992 T1 COCAINE AND OTHER COMMONLY ABUSED DRUGS T2 Harrison's Neurology in Clinical Medicine, 4e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259835865 LK neurology.mhmedical.com/content.aspx?aid=1147191992 RD 2024/04/20 AB The abuse of cocaine and other psychostimulants reflects a complex interaction between the pharmacology of the drug, the personality and expectations of the user, and the environmental context in which the drug is used1. Polydrug abuse involving the concurrent use of several drugs with different pharmacologic effects is increasingly common. Sometimes one drug is used to enhance the effects of another, as with the combined use of cocaine and nicotine, benzodiazepines and methadone, or cocaine and heroin in methadone-maintained patients. Some forms of polydrug abuse, such as the combined use of IV heroin and cocaine, are especially dangerous and account for many hospital emergency room visits.