RT Book, Section A1 Nguyen, Benjamin A1 Thottakara, John A1 Bell, Kathleen R. A2 Mitra, Raj SR Print(0) ID 1162856625 T1 Patient Management for Traumatic Brain Injury T2 Principles of Rehabilitation Medicine YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071793339 LK neurology.mhmedical.com/content.aspx?aid=1162856625 RD 2024/11/11 AB Moderate to severe traumatic brain injury (TBI) is a leading cause of morbidity and mortality in the United States and worldwide, with an annual incidence of 60 to 100 per 100,000.1–4 In 2010, there were 715.7 per 100,000 emergency department (ED) visits related to TBI, with 91.7 per 100,000 TBI-related hospitalizations, and 17.1 per 100,000 TBI-related deaths.5 It is estimated that over 5 million people in the United States are living with TBI-related disability,6 and by 2020, TBI will be the third leading cause of disability in the world,7 with the annual cost of providing acute and rehabilitation care for individuals in North America projected to be in the billions of dollars.8 These statistics are especially troublesome because the incidence of TBI is highest among young males between the ages of 15 and 24,1,8,9 leading to decades of disability and lost productivity. Despite the improvement in mortality rate, many survivors are left with lifelong impairments in physical, cognitive, and psychosocial functioning. Management of these individuals is challenging, given the varying severity of illness and baseline comorbidities.