RT Book, Section A1 Feldman, Dorianne R. A1 Van, Stephanie A1 Edmiston, Travis A1 Mayer, R. Samuel A2 Mitra, Raj SR Print(0) ID 1159836115 T1 Rehabilitation of the Organ Transplant Patient T2 Principles of Rehabilitation Medicine YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071793339 LK neurology.mhmedical.com/content.aspx?aid=1159836115 RD 2024/04/18 AB ORGAN TRANSPLANTATION IS ONE OF THE MOST complex surgical procedures in modern medicine. In 1954, Dr. Joseph Murray and Dr. David Hume of Brigham Hospital in Boston first successfully transplanted a human kidney from a living donor to his identical twin recipient. In 1967, Dr. Christiaan Barnard in Cape Town, South Africa, was the first to perform a human heart transplant. Notably, in the 1970s, Dr. Jean-Francois Borel discovered cyclosporine, a derivative of soil fungus that remains a key component in most transplant patients’ immunosuppressive therapy regimens today. These initial efforts did not have encouraging survival rates and over the next few decades, advances in immunosuppressant therapies and tissue typing helped to improve transplant procedure outcomes and prolong survival. Given that transplant patients are surviving longer, the ultimate goal of organ transplantation, recovery, and rehabilitation is to return these patients to the highest level of function and livelihood as possible.