RT Book, Section A1 Waxman, Stephen G. SR Print(0) ID 1186189843 T1 Vascular Supply of the Brain T2 Clinical Neuroanatomy, 29e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260452358 LK neurology.mhmedical.com/content.aspx?aid=1186189843 RD 2024/04/19 AB It is essential for all clinicians to be familiar with vascular disease of the brain. The brain and spinal cord are critically dependent on an uninterrupted supply of oxygenated blood, and thus are dependent on uninterrupted flow through the cerebral vessels. About 18% of the total blood volume in the body circulates in the brain, which accounts for about 2% of the body weight. The blood transports oxygen, nutrients, and other substances necessary for proper functioning of the brain and carries away metabolites. Loss of consciousness occurs in less than 15 seconds after blood flow to the brain has stopped, and irreparable damage to the brain tissue occurs within 5 minutes.