RT Book, Section
A1 Eitan, Renana
A1 Silbersweig, David A.
A2 Silbersweig, David A.
A2 Safar, Laura T.
A2 Daffner, Kirk R.
SR Print(0)
ID 1178761904
T1 Mood, Psychotic, Anxiety, and Obsessive-Compulsive Disorders: A Neuropsychiatric Foundation 
T2 Neuropsychiatry and Behavioral Neurology: Principles and Practice
YR 2021
FD 2021
PB McGraw Hill
PP New York, NY
SN 9781260117103
LK neurology.mhmedical.com/content.aspx?aid=1178761904
RD 2024/04/19
AB Contemporary  neuropsychiatry  conceptualizes  mental  illnesses  as  brain  disorders.  In  contrast  to  neurological  disorders  with  identifiable  lesions,  mental  disorders  can  be  addressed  as  disorders  of  brain  circuits.  The  view  of  mental  disorders  as  brain  circuit  disorders  has  been  further  consolidated  by  reports  on  successful  treatment  of  mental  disorders  with  focal  brain  interventions.  However,  mental  illnesses  not  only  originate  from  dysfunction  of  different  brain  areas  but  also  represent  a  much  more  complex  multidimensional  organization  of  information  in  the  brain.  The  basic  biological  science  behind  some  of  the  fundamental  elements  of  mental  illness,  such  as  cognition,  emotion,  behavior,  and  social  processes,  has  been  advancing  rapidly  in  the  past  20  years.  New  scientific  methods  for  studying  the  brain  include  structural  and  functional  imaging  of  distinct  neural  circuit  elements  and  connections.  Genetic  techniques  have  identified  risk  factors  for  mental  illness.  Novel  analytic  techniques  such  as  neural  networks,  a  biologically  inspired  programming  paradigm  which  enables  learning  from  observational  data,  have  partially  revealed  the  basic  neural  mechanisms  underlying  mental  illness.1  However,  clinical  research  supporting  the  classification  system  in  psychiatry  has  not  kept  up  with  these  scientific  advances.2,3  Psychiatric  diagnoses  are  currently  distinguished  based  on  sets  of  specific  symptoms  as  detailed  in  the  Diagnostic  and  Statistical  Manual  of  Mental  Disorders,  5th  edition  (DSM-5),  released  in  2013.4  In  2009,  the  National  Institute  of  Mental  Health  (NIMH)  launched  the  research  domain  criteria  (RDoC)  project  to  develop,  for  research  purposes,  new  ways  of  classifying  mental  disorders  based  on  dimensions  of  observable  behavior  and  neurobiological  measures.5  Integration  of  clinical  experience  with  the  rapid  advancing  neurobiological  knowledge  is  essential  for  every  treatment  provider  in  the  field  of  psychiatry  and  neuropsychiatry.6