RT Book, Section
A1 Salama, Kate
A1 O’Neal, Mary
A1 Nathan, Margo
A1 Mittal, Leena
A2 Silbersweig, David A.
A2 Safar, Laura T.
A2 Daffner, Kirk R.
SR Print(0)
ID 1178765035
T1 Women’s Neuropsychiatry
T2 Neuropsychiatry and Behavioral Neurology: Principles and Practice
YR 2021
FD 2021
PB McGraw Hill
PP New York, NY
SN 9781260117103
LK neurology.mhmedical.com/content.aspx?aid=1178765035
RD 2024/04/18
AB Women’s  neurology  and  mental  health  are  defined  as  the  study  of  neurologic  and  psychiatric  disorders  approached  through  a  sex-based  lens.  This  chapter  will  discuss  some  of  the  sex-based  differences  in  neurologic  and  psychiatric  disorders.  The  specific  concerns  vary  depending  on  the  disorder,  where  the  woman  is  in  her  reproductive  cycle,  and  her  psychosocial  milieu.  The  neurologic  diseases  to  be  reviewed  are  those  with  significant  sex  differences  in  prevalence,  clinical  presentation,  or  management.  They  include  systemic  lupus  erythematosus  (SLE),  migraine,  epilepsy,  anti-N-methyl-D-aspartate  receptor  (NMDAR)  encephalitis,  stroke,  and  Alzheimer’s  disease  (AD).  The  psychiatric  disorders  to  be  discussed  will  include  those  that  are  related  to,  or  influenced  by,  the  reproductive  events  in  a  woman’s  life—including  perimenstrual  disorders,  perinatal  disorders,  and  perimenopausal  disorders.  We  will  focus  on  these  periods  of  increased  hormonal  variability  and  discuss  the  relationship  between  sex  hormones  and  serotonergic,  dopaminergic,  GABAergic,  and  glutamatergic  transmission,  and  other  neurobiological  factors.  While  the  focus  of  this  chapter  is  on  the  sex  differences  in  epidemiology,  clinical  features,  pathophysiology,  and  treatment  of  many  neurologic  and  psychiatric  disorders,  it  is  important  to  note  that  these  same  disorders  are  covered  in  detail  in  other  chapters  of  this  textbook.  We  direct  the  reader  to  the  specific  chapters,  as  appropriate,  within  each  of  the  subtitles  below.