RT Book, Section A1 Zygmunt, Alexander M. A1 Tian, Cuixia A2 Hershey, Andrew D. SR Print(0) ID 1195238413 T1 Myasthenia Gravis and Related Disorders of the Neuromuscular Junction T2 CURRENT Diagnosis & Treatment Pediatric Neurology YR 2023 FD 2023 PB McGraw Hill Education PP New York, NY SN 9781260457520 LK neurology.mhmedical.com/content.aspx?aid=1195238413 RD 2024/10/06 AB Pediatric disorders of the neuromuscular junction (NMJ), a group of disorders that affect the structure, function, or both the structure and function of the NMJ, can be acquired or congenital. Patients with NMJ disorders typically present with weakness that fluctuates throughout the day and is fatigable in nature. Classically, fluctuating weakness affects extraocular musculature early in the disease course, causing symptoms such as fluctuating ptosis or diplopia. Bulbar weakness is also commonly described in NMJ disorders, which can present as difficulty swallowing, choking, gagging, weak crying, nasal-sounding voice, or neck flexion or extension weakness.