RT Book, Section
A1 Wilkinson, Jayne R.
A1 Weintraub, Daniel
A1 Stern, Matthew B.
A2 Watts, Ray L.
A2 Standaert, David G.
A2 Obeso, Jose A.
SR Print(0)
ID 55793554
T1 Chapter 13. Clinical Manifestations of Parkinson's Disease
T2 Movement Disorders, 3e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-161312-5
LK neurology.mhmedical.com/content.aspx?aid=55793554
RD 2024/04/18
AB James  Parkinson's  original  1817  description  of  the  “shaking  palsy”  remains  a  remarkably  accurate  account  of  the  disease  now  bearing  his  name.1  Although  the  cardinal  manifestations  of  Parkinson's  disease  (PD)  are  no  different  today,  our  understanding  of  the  full  array  of  parkinsonian  signs  and  symptoms  continues  to  grow.  In  addition  to  motor  symptoms,  the  nonmotor  symptoms  of  PD  are  now  recognized  as  a  significant  source  of  disability.2  Given  continuing  advances  in  therapy,  it  is  increasingly  important  that  clinicians  recognize  PD  in  its  earliest  stages.  Equally  critical,  PD  must  be  distinguished  from  less  common  forms  of  parkinsonism  because  prognosis  and  treatment  may  differ.  In  this  chapter,  we  discuss  the  motor  and  nonmotor  clinical  manifestations  of  PD,  followed  by  a  discussion  of  clinical  signs  that  can  distinguish  PD  from  other  parkinsonian  syndromes.