RT Book, Section A1 Ropper, Allan H. A1 Samuels, Martin A. A1 Klein, Joshua P. SR Print(0) ID 57616425 T1 Chapter 9. Other Somatic Sensation T2 Adams and Victor's Principles of Neurology, 10e YR 2014 FD 2014 PB The McGraw-Hill Companies PP New York, NY SN 978-0071794794 LK neurology.mhmedical.com/content.aspx?aid=57616425 RD 2023/03/28 AB Sensory and motor functions are interdependent, as was dramatically illustrated by the early animal experiments of Claude Bernard and Charles Sherrington, in which practically all effective movement of a limb was abolished by eliminating only its sensory innervation (sectioning of posterior roots). Interruption of other sensory pathways and destruction of the parietal cortex also has profound effects on motility. To a large extent, human motor activity depends on a constant influx of sensory impulses (most of them not consciously perceived). Sensory motor integration is therefore necessary for normal nervous system function but disease may affect motor or sensory functions independently. There may be loss or impairment of sensory function, and this can represent the principal manifestation of neurologic disease.