RT Book, Section
SR Print(0)
ID 1101677912
T1 Signaling at the Nerve-Muscle Synapse: Directly Gated Transmission
T2 Principles of Neural Science, Fifth Edition
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-139011-8
LK neurology.mhmedical.com/content.aspx?aid=1101677912
RD 2024/04/20
AB The  Neuromuscular  Junction  Is  a  Well-Studied  Example  of  Directly  Gated  Synaptic  TransmissionThe  Motor  Neuron  Excites  the  Muscle  by  Opening  Ligand-Gated  Ion  Channels  at  the  End-PlateThe  End-Plate  Potential  Is  Produced  by  Ionic  Current  Through  Acetylcholine  Receptor-ChannelsThe  Ion  Channel  at  the  End-Plate  Is  Permeable  to  Both  Sodium  and  PotassiumThe  Current  Through  Single  Acetylcholine  Receptor-Channels  Can  Be  Measured  Using  the  Patch  ClampIndividual  Receptor-Channels  Conduct  All-or-None  Unitary  CurrentsFour  Factors  Determine  the  End-Plate  CurrentThe  Molecular  Properties  of  the  Acetylcholine  Receptor-Channel  Are  KnownAn  Overall  ViewPostscript:  The  End-Plate  Current  Can  Be  Calculated  from  an  Equivalent  Circuit