RT Book, Section A1 Amato, Anthony A. A1 Russell, James A. SR Print(0) ID 1115660550 T1 Other Disorders of Neuromuscular Transmission T2 Neuromuscular Disorders, 2e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071752503 LK neurology.mhmedical.com/content.aspx?aid=1115660550 RD 2024/03/29 AB This chapter describes the disorders of neuromuscular transmission (DNMT) other than myasthenia gravis (MG) (Table 26-1). The neuromuscular junction (NMJ) is a physiologically complex structure. Its ability to function optimally requires the integration of a large number of proteins including ion channels that are correctly configured and distributed. As a result of numerous potential sites of vulnerability, DNMTs may occur as a consequence of multiple, albeit infrequent disorders. Autoimmune, genetic, or toxic mechanisms may disrupt the ultrastructure or physiology of the NMJ, thus interfering with effective NMT.