Print Get Citation Citation Disclaimer: These citations have been automatically generated based on the information we have and it may not be 100% accurate. Please consult the latest official manual style if you have any questions regarding the format accuracy. AMA Citation Chan A, Cheung A. Chan A, & Cheung A Chan, Alex, and Andrew Cheung. Bariatric surgery and long-term survival in patients with obesity and end-stage kidney disease. 2 Minute Medicine, 12 June 2020. McGraw-Hill, 2020. AccessNeurology. https://neurology.mhmedical.com/updatesContent.aspx?gbosid=550734§ionid=248110332APA Citation Chan A, Cheung A. Chan A, & Cheung A Chan, Alex, and Andrew Cheung. (2020). Bariatric surgery and long-term survival in patients with obesity and end-stage kidney disease. (2020). 2 minute medicine. McGraw-Hill. https://neurology.mhmedical.com/updatesContent.aspx?gbosid=550734§ionid=248110332.MLA Citation Chan A, Cheung A. Chan A, & Cheung A Chan, Alex, and Andrew Cheung. "Bariatric surgery and long-term survival in patients with obesity and end-stage kidney disease." 2 Minute Medicine McGraw-Hill, 2020, https://neurology.mhmedical.com/updatesContent.aspx?gbosid=550734§ionid=248110332. Download citation file: RIS (Zotero) EndNote BibTex Medlars ProCite RefWorks Reference Manager Mendeley © Copyright Clip Full Chapter Figures Only Tables Only Videos Only Supplementary Content Top Bariatric surgery and long-term survival in patients with obesity and end-stage kidney disease by Alex Chan, Andrew Cheung, MD MBA Listen +Originally published by 2 Minute Medicine® (view original article). Reused on AccessMedicine with permission. +1. Bariatric surgery for patients with obesity and end-stage kidney disease was associated with lower all-cause mortality at 5 years. +Evidence Rating: 2 (Good) +Obesity and end-stage kidney disease are significant causes of mortality and morbidity in North America, and represents a significant burden to the healthcare system. Bariatric Surgery has been associated with lower risks of hyperglycaemia, hypertension, and adverse cardiovascular events in patients with obesity and type 2 diabetes. In patients with end-stage renal disease (ESRD) however, bariatric surgery rates remain low due to speculation of surgical complications and lack of literature demonstrating a clear benefit. To further investigate the benefits or harms of bariatric surgery for obese ESRD patients, researchers conducted a retrospective cohort study with data from the United States Renal Data System registry. Specifically, Cox proportional hazards analysis was used to evaluate differences in long-term survival among 1597 surgical and a matched cohort of 4750 nonsurgical patients with ESRD and obesity. Bariatric surgery was associated with lower all-cause mortality at 5 years compared with standard care (cumulative incidence, 25.6% vs. 39.8%; hazard ratio, 0.69, 95% CI, 0.60-0.78), primarily driven by lower rates of cardiovascular causes (cumulative incidence, 8.4% vs. 17.2%; hazard ratio, 0.51; 95% CI, 0.41-0.65). Interestingly however, bariatric surgery was associated with higher all-cause mortality at one year (cumulative incidence, 8.6% vs. 7.7%; hazard ratio, 1.45; 95% CI, 1.13-1.85), and increase in kidney transplant at 5 years (cumulative incidence, 33.0% vs. 20.4%; adjusted hazard ratio, 1.82; 95% CI, 1.58-2.09). This population-based study of patients with obesity and ESRD found a long term mortality benefit associated with bariatric surgery. Although further investigations need to be carried out to better meaningfully sort out the possible health benefits of bariatric surgery, findings suggest that the health benefits of surgery for patients with obesity can be generalized with patients with concomitant ESRD. +Click to read the study in JAMA Surgery +©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.