Print Get Citation Citation Disclaimer: These citations have been automatically generated based on the information we have and it may not be 100% accurate. Please consult the latest official manual style if you have any questions regarding the format accuracy. AMA Citation Lennon J, Chan A. Lennon J, & Chan A Lennon, Jack, and Alex Chan. COVID-19 associated with a wide range of cardiac manifestations in pediatric patients. 2 Minute Medicine, 1 October 2020. McGraw-Hill, 2020. AccessNeurology. https://neurology.mhmedical.com/updatesContent.aspx?gbosid=553769§ionid=250444988APA Citation Lennon J, Chan A. Lennon J, & Chan A Lennon, Jack, and Alex Chan. (2020). Covid-19 associated with a wide range of cardiac manifestations in pediatric patients. (2020). 2 minute medicine. McGraw-Hill. https://neurology.mhmedical.com/updatesContent.aspx?gbosid=553769§ionid=250444988.MLA Citation Lennon J, Chan A. Lennon J, & Chan A Lennon, Jack, and Alex Chan. "COVID-19 associated with a wide range of cardiac manifestations in pediatric patients." 2 Minute Medicine McGraw-Hill, 2020, https://neurology.mhmedical.com/updatesContent.aspx?gbosid=553769§ionid=250444988. Download citation file: RIS (Zotero) EndNote BibTex Medlars ProCite RefWorks Reference Manager Mendeley © Copyright Clip Full Chapter Figures Only Tables Only Videos Only Supplementary Content Top COVID-19 associated with a wide range of cardiac manifestations in pediatric patients by Jack Lennon, Alex Chan Listen +Originally published by 2 Minute Medicine® (view original article). Reused on AccessMedicine with permission. +1. Pediatric patients during the COVID-19 pandemic present with a wide range of cardiac manifestations that require early detection and treatment. +Evidence Rating Level: 2 (Good) +The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has resulted in increased hyperinflammatory presentations in otherwise healthy children. This international, multi-center, retrospective chart review examined cardiac manifestations in a pediatric cohort with multi-system inflammatory syndrome (MIS-C) occurring during the SARS-CoV2 pandemic. A total of 55 children from five countries met inclusion criteria (M [SD] age = 7.0 [5.2] years). A total of 27 patients (49%) required ICU admission, 35 patients (64%) had evidence of myocardial dysfunction (left ventricular ejection fraction [LVEF] < 60%), 24 patients (44%) had evidence of shock, and 2 patients (4%) did not survive. A total of 11 patients (20% met full criteria for Kawasaki disease and had lower NT pro-BNP (M [SD] = 1,606 [1,089], p = 0.007), ferritin (M [SD] = 171 , p = 0.008), and D-dimer (M [SD] = 1.4 [0.7], p = 0.025) levels compared to those not meeting full diagnostic criteria. Patients with full Kawasaki criteria, compared to others, were also younger (M [SD] age = 5.4 [5.7] years, p = 0.01), experienced longer fevers (M [SD] length = 6.3 [1.3] days, p = 0.07), and better LVEF (LVEF 58 [9%], p = 0.05). Overall, this study highlights the spectrum of cardiac manifestations among pediatric patients during the SARS-CoV2 pandemic, allowing for better detection and preparation for treatment in clinical settings. +Click to ready the study in JAHA +©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.